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LC3 conjugation onto the phagosome membrane enables its fusion with the lysosome, promoting the degradation of the phagosomes content [17], demonstrating the versatility of efferocytosis, as it can utilize components of other cellular processes to clear apoptotic cells efficiently

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Multivariate analysis demonstrated that TxNIP is an independent prognostic factor ( P =0.014, HR=0.2, 95% CI=0.10.7) and, of note, independent of oestrogen receptor status ( P =0.001, HR=0.1, 95% CI=0.00.3) (Table 2)

1 Targets Damaged Tissue BPC-157 binds to growth factor receptors in injured areas, initiating a cascade of healing signals

Among them, several genes seemed to be involved in mitochondrial metabolism and oxidative stress, as e.g., SLC25A39